2018年10月16日星期二

How do tudca is produced!

Tudca can be natually found in bear gall,but this is very rare and costly.So Tauroursodeoxycholic acid was developed by Bruschettini S. r of Italy at very the first time.With the development of pharmaceutical preparation technology,tudca can be easily gained from chemical synthesis.

The main raw materials to produce tudca is udca, it is kind of combined bile acid comes from reactant of udca and the amino of taurine. Udca is also by synthesis of animal bile acids such as chenodeoxycholic acid is the most used one.This means tudca prepared in this way inevitably contains a certain amount of Taurochenodeoxycholic acid. CHP request udca has been controlled content of chenodeoxycholic acid and lithocholic acid which will bring tudca Chenodeoxycholic Acid and taurolithocholic acid.The two content of tudca are important test indicators ot its quality and purity.

Next time,we will see the impurity of Tudca.


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