Tudca can be natually found in bear gall,but
this is very rare and costly.So Tauroursodeoxycholic acid was developed
by Bruschettini S. r of Italy at very the first time.With the development of pharmaceutical
preparation technology,tudca can be easily gained from chemical synthesis.
The main raw materials to produce tudca is
udca, it is kind of combined bile acid comes from reactant of udca and the
amino of taurine. Udca is also by synthesis of animal bile acids such as
chenodeoxycholic acid is the most used one.This means tudca prepared in
this way inevitably contains a certain amount of Taurochenodeoxycholic
acid. CHP request udca has been controlled content of chenodeoxycholic acid and
lithocholic acid which will bring tudca Chenodeoxycholic Acid and taurolithocholic
acid.The two content of tudca are important test indicators ot its quality and
purity.
Next time,we will see the impurity of Tudca.
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